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Nanoparticles
for Pharmaceutical Applications
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Edited
by
A. J.
Domb, Y. Tabata, M. N. V. Ravi Kumar, and S. Farber
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January
2007
500 pages, Hardcover
ISBN: 1-58883-089-6
US$399.00 |
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DESCRIPTION |
| Nanoparticles
for Pharmaceutical Applications deals with emerging new
technologies for developing customized solutions for drug delivery
systems. The drug delivery systems should positively impact the rate
of absorption, distribution, metabolism, and excretion of the drug
or other related chemical substances in the body. In addition, the
drug delivery system should allow the drug to bind to its target
receptor and influence that receptor’s signaling and activity.
Drug delivery materials should be compatible, easy to bind with a
particular drug, and able to degrade into fragments after use that
are either metabolized or driven out via normal excretory routes.
The book emphasizes the material-based technologies in the area of
drug delivery that include solid lipid nanoparticles, liposomes,
polysaccharides, polyesters, micelles, etc. The different
route-based delivery systems such as oral, pulmonary, ocular,
dermal, etc. are discussed. The focus is also on certain diseases to
which these technologies can be applied for maximum benefits:
cancer, tuberculosis, restenosis, etc. The topics also include gene
and vaccine delivery as well as safety concerns of these nano-scale
materials. The 22 state-of-the-art review chapters are written by
world-renowned scientists working in the field of
nanotechnology-based drug delivery systems. |
| CONTENTS |
- Recent Advances in
Polyalkylcyanoacrylate Nanoparticles for Drug Delivery, Elias
Fattal, Karine Andrieux, Gillian Barratt, Patrick Couvreur,
Denis Labarre, Gilles Ponchel, and Christine Vauthier
- Dendrimers and Hyperbranched Nanospheres
with Medical Applications, Sõnke Svenson, and Donald
A. Tomalia
- Lipid Nanoparticles (SLN and NLC) for
Drug Delivery, Eliana B. Souto and Rainer H. Müller
- Liposomes for Drug Delivery, Pierre
Simard, Jean-Christophe Leroux, Christine Allen, and Olivier
Meyer
- Polysaccharide-based Nanoparticles as
Carriers for Drug and Vaccine Delivery, María José
Alonso, Cecilia Prego, and Marcos García-Fuentes
- The Impact of Surface Charge on
Nanoparticle Performance, Oshrat Harush, Yoram Altschuler,
and Simon Benita
- Surface Modification of Nanoparticulate
Drug Carriers, Vladimir P. Torchilin
- Polymeric Micelles as Nano-sized Drug
Carrier Systems, Masayuki Yokoyama
- Polyester Nano- and Micro-particles by
Polymerization and by Self-assembly of Macromolecules, Stanislaw
Slomkowski
- Characterization of Novel Intranasal
Sustained-Release Nanoparticles for Delivery of Neuropeptides to
the Brain, Michael J. Kubek, Michael Yard, Debomoy K.
Lahiri, and Abraham J. Domb
- Nanoparticles in Ocular Drug Delivery,
Esther Eljarrat Binstock and Abraham J. Domb
- Oral Drug Delivery, V. Bhardwaj and
M. N. V. Ravi Kumar
- Lymphatic Absorption of Nanoparticles,
Pavel Gershkovich, Leonid Kagan, and Amnon Hoffman
- Nanoparticles Aiming at Specific
Targets--Dermal and Transdermal Delivery, Biana Godin and
Elka Touitou
- Nanoparticles for Respiratory Drug
Delivery, R. Banerjee
- Nanoparticles of Biodegradable Polymers
for Cancer Chemotherapy, Si-Shen Feng, Priscilla Pui Sze
Lee, and Khin Yin Win
- Nanoparticles for the Treatment of
Restenosis, Einat Cohen-Sela, M. Chorny, and G. Golomb
- Nanostructured Polycation Materials for
Gene Delivery, I. Yudovin-Farber and A. J. Domb
- Nanotechnology: Implications for
Antitubercular Chemotherapy, Rajesh Pandey and G. K. Khuller
- Gelatin-based Nanomicelles, Toshihiro
Kushibiki and Yasuhiko Tabata
- Carbon Nanotubes: Role in Healthcare,
Lalit M. Bharadwaj and Vijayender Bhalla
- Toxicity Issues Related to
Nanoparticulate Systems, Rajendra Pawar, Sudhakar Bhusare,
and Yeshwant Vibhute
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| READERSHIP |
| This
book is a valuable reference source for scientists, graduate
students, engineers, industrial researchers, and other professionals
working in the fields of pharmaceutical sciences, medicine,
medicinal chemistry, drug delivery, clinical pharmacology,
biotechnology, bionanotechnology, polymer science, materials
science, chemistry, chemical biology, chemical engineering,
biochemistry, biological engineering, biomedical sciences, and other
related areas of life sciences. |
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