–––––––––––––––––––––––––––––––––––– REVIEW––––––––––––––––––––––––––––––––––––
Clustered Regularly Interspaced Short Palindromic Repeats System of Genome
Engineering in Embryos to Repair Genes
Firoozeh Niazvand, Zohre Fathinezhad, Narjes Alfuraiji, Enas Abdalla Etajuri, Fatemeh Amini-Chermahini,
Mohammad Chehelgerdi, and Reza Ranjbar
J. Biomed. Nanotechnol. 17, 331–356 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

–––––––––––––––––––––––––––––––––––– ARTICLES ––––––––––––––––––––––––––––––––––––
Delivery of Ferulic Acid with PEGylated Diphenylalanine- Based Nanoparticles for the
Treatment of Arthritis in Early Stage
Liming He, Yingchun Zeng, Xianyan Qin, Lihua Pan, Tao Chen, Qin Wang, Yiping Ma, and Jiyu Fang
J. Biomed. Nanotechnol. 17, 357–368 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Transcriptome Analysis of the Molecular Mechanism of Bacteriocin Synthesis in
Lactobacillus plantarum KLDS1.0391 Under Nanoparticle NaCl Stress
Le Zhao, Penghao Zhao, Jiacui Shang, and Xiangchen Meng
J. Biomed. Nanotechnol. 17, 369–381 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Polyethyleneimine-a-Tocopherol Hydrogen Succinate/Hyaluronic Acid-Quercetin
(PEI-TOS/HA-QU) Core–Shell Micelles Delivering Paclitaxel for Combinatorial
Treatment of MDR Breast Cancer
Jin Qian, Shuo Liu, Tianshu Yang, Yi Xiao, Jiabin Sun, Juanjuan Zhao, Ze'an Zhang, and Yan Xie
J. Biomed. Nanotechnol. 17, 382–398 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Core–Shell Poly(l-lactic acid)-Hyaluronic Acid Nanofibers for Cell Culture and Pelvic
Ligament Tissue Engineering
Di Zhang, Xiaobo Huang, Huaiming Wang, Yingqi Wei, Zifeng Yang, Rongkang Huang, Weiwen Liang, Xiusen Qin, Wentai Guo,
Donglin Ren, Lin Jin, Xianhan Jiang, and Hui Wang
J. Biomed. Nanotechnol. 17, 399–406 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Fast and Accurate Control Strategy for Portable Nucleic Acid Detection (PNAD) System
Based on Magnetic Nanoparticles
Yile Fang, Haoran Liu, Yue Wang, Xiangyi Su, Lian Jin, Yanqi Wu, Yan Deng, Song Li, Zhu Chen, Hui Chen, and Nongyue He
J. Biomed. Nanotechnol. 17, 407–415 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Illumina Sequencing Reveals Conserved and Novel MicroRNAs of Dendrobium nobile
Protocorm Involved in Synthesizing Dendrobine, a Potential Nanodrug
Xu Qian, Jieying Zhu, Qingjun Yuan, Qi Jia, Hui Jin, Jing Han, Surendra Sarsaiya, Leilei Jin, Jishuang Chen, and Lanping Guo
J. Biomed. Nanotechnol. 17, 416–425 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Functional Exosome-Mediated Delivery of Triptolide Endowed with Targeting
Properties as Chemotherapy Carriers for Ovarian Carcinoma
Di He, Xiaoyi Xu, Longxia Li, Chuanrong Chen, Ke Gong, Qianqian Guo, Fangfang Liu, Yingbin Wang, Yourong Duan, and He Li
J. Biomed. Nanotechnol. 17, 426–438 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Preparation of Core–Shell Silica Microspheres with Controllable Shell Thickness for
Fast High Performance Liquid Chromatography Separation of Alkyl Benzenes
and Intact Proteins
Hongjun Xia, Huaiming Wang, Jianshan Wang, Lin Wang, Lin Jin, and Quan Bai
J. Biomed. Nanotechnol. 17, 439–446 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Anti-Human Epidermal Growth Factor Receptor 2 Single-Chain Fv Fragment-Decorated
DM1 Nanoparticles for Specific Targeting of Human Epidermal Growth Factor Receptor
2-Positive Breast Tumor Cells
Ling Ni and You-Xin Li
J. Biomed. Nanotechnol. 17, 447–455 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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A Synthetic Biodegradable Polymer Membrane for Guided Bone Regeneration in Bone Defect
Kangjie Ma, Dongmei Mei, Xiaodong Lin, Li Zhang, Jie Gao, Xiaojing Li, Xuechen Zhu,Qiao Jin, Shuang Zhang,
Hao Xu, and Baodong Zhao
J. Biomed. Nanotechnol. 17, 456–465 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Interferon Regulatory Factor 5 siRNA-Loaded Folate-Modified Cationic Liposomes
for Acute Lung Injury Therapy
Qin Xu, Mengran Guo, Xiaodong Jin, Quansheng Jin, Zhongshan He, Wen Xiao, Wei Zou, Ruiling Xu, Lizhi Cheng, Siyan He,
Lili Cao, Mostafa A. Elbahnasawy, Wentao Peng, Chunling Jiang, and Xiangrong Song
J. Biomed. Nanotechnol. 17, 466–476 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Nano-TiO₂ Reduces Testosterone Production in Primary Cultured Leydig Cells
from Rat Testis Through the Cyclic Adenosine Phosphate/Cyclic Guanosine
Phosphate/Epidermal Growth Factor Receptor/Matrix Metalloproteinase Signaling Pathway
Fashui Hong, Xiao Ze, Lingjuan Li, and Yuguan Ze
J. Biomed. Nanotechnol. 17, 477–486 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Construction of Intelligent Nano-Drug Delivery System for Targeting Extranodal Nasal
Natural Killer/Thymus Dependent Lymphocyte
Xinyu Zhang, Jun Wu, and Dongjun Lin
J. Biomed. Nanotechnol. 17, 487–500 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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A Photothermal Therapy Strategy for Monitoring Real-Time Temperature in Kidney
Cancers by Injecting Gold Nanorods with Phosphors
Wenzeng Shen, Xuefeng Zhang, Dongyang Liu, Christina Xing, Isabelle Tucker, Eric Amador, Wei Chen, and Yanmin Yang
J. Biomed. Nanotechnol. 17, 501–508 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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–––––––––––––––––––––––––––––––––––– REVIEWS ––––––––––––––––––––––––––––––––––––
Understanding and Regulating Cell-Matrix Interactions Using Hydrogels of
Designable Mechanical Properties
Jiapeng Yang, Yu Zhang, Meng Qin, Wei Cheng, Wei Wang, and Yi Cao
J. Biomed. Nanotechnol. 17, 149–168 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Temperature Plays an Essential Regulatory Role in the Tumor Immune Microenvironment
Bin Zhang, Youpeng Wang, Ziyin Zhao, Bing Han, Jinbo Yang, Yang Sun, Bingyuan Zhang, Yunjin Zang, and Huashi Guan
J. Biomed. Nanotechnol. 17, 169–195 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

–––––––––––––––––––––––––––––––––––– ARTICLES ––––––––––––––––––––––––––––––––––––
RNA Sequencing Evidences the Prevention of Oxidative Stress is Effective in Injury-Induced
Heterotopic Ossification Treatment
Kai Xie, Lijun Chen, and Jiazhao Yang
J. Biomed. Nanotechnol. 17, 196–204 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Folic Acid Functionalized Chlorin e6-Superparamagnetic Iron Oxide Nanocarriers as a
Theranostic Agent for MRI-Guided Photodynamic Therapy
Zhenbo Sun, Mingfang Luo, Jia Li, Ailing Wang, Xucheng Sun, Qiong Wu, Kaiyue Li, Ying Ma, Caixia Yang, and Xianglin Li
J. Biomed. Nanotechnol. 17, 205–215 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Novel Copper Nanoparticles Intercalated Polyurethane Heparin/Poly-L-Lysine Chelates
Coated Stents: Viability Study for Coronary Vascular Cells and Aneurysms Treatments
Ji Ma, Teng-Fei Li, and Hui-Feng Yuan
J. Biomed. Nanotechnol. 17, 216–229 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Quercetin Nanoparticle Ameliorates Lipopolysaccharide-Triggered Renal Inflammatory
Impairment by Regulation of Sirt1/NF-KB Pathway
Shan Lu, Shuai Zhou, Juwu Chen, Jian Zheng, Jia Ren, Peiyi Qi, Zhiqiang Zhu, and Zhenzhen Li
J. Biomed. Nanotechnol. 17, 230–241 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Development of Gelatin-Silk Sericin Incorporated with Poly(vinyl alcohol) Hydrogel-Based
Nanocomposite for Articular Cartilage Defects in Rat Knee Joint Repair
Ji-Jun Zhao, Dong-Cheng Liu, Ying-Hao Yu, and Hongtao TangJi-Jun Zhao, Dong-Cheng Liu, Ying-Hao Yu, and Hongtao Tang
J. Biomed. Nanotechnol. 17, 242–252 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Innovative Mucoadhesive Precursor of Liquid Crystalline System Loading
Anti-Gellatinolytic Peptide for Topical Treatment of Oral Cancer
Giovana Maria Fioramonti Calixto, Francesca Damiani Victorelli, Michelle Franz-Montan, Fátima Baltazar, and Marlus Chorilli
J. Biomed. Nanotechnol. 17, 253–262 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Development of ¹⁷⁷Lu-DN(C19)-CXCR4 Ligand Nanosystem for Combinatorial Therapy
in Pancreatic Cancer
Maydelid Trujillo-Nolasco, Pedro Cruz-Nova, Guillermina Ferro-Flores, Brenda Gibbens-Bandala, Enrique Morales-Avila,
Liliana Aranda-Lara, Miguel Vargas, and Blanca Ocampo-García
J. Biomed. Nanotechnol. 17, 263–278 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Protective Effect of Mitochondrially Targeted Peptide Against Oxidant Injury of Cone
Photoreceptors Through Preventing Necroptosis Pathway
Yuan He, Yun Xu, Zejun Chen, Beilei He, Zhuoya Quan, Ruixue Zhang, and Yuan Ren
J. Biomed. Nanotechnol. 17, 279–290 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Microvesicles from Schwann-Like Cells as a New Biomaterial Promote Axonal Growth
Kai Ye, Jiahong Yu, Li Li, Hui Wang, Bin Tang, Wei Ni, Jiqin Zhou, Yating Ling, Xiaorui Lu, Dongdong Niu,
Murugan Ramalingam, and Jiabo Hu
J. Biomed. Nanotechnol. 17, 291–302 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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A Highly Cellular Uptake Ternary Nanocomposite Titanate Nano-Tubes/CuFe₂O₄/Zn–Fe
Could Induce Intrinsic Apoptosis of Prostate Cancer Cells: An Extended Study
Ahmed A. G. El-Shahawy
J. Biomed. Nanotechnol. 17, 303–311 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Highly Fluorescent N-Doped Carbon Quantum Dots Derived from Bamboo Stems for
Selective Detection of Fe³⁺ Ions in Biological Systems
Jiamin Yan, Yuneng Lu, Shaowen Xie, Haihu Tan, Weilan Tan, Na Li, Lijian Xu, and Jianxiong Xu
J. Biomed. Nanotechnol. 17, 312–321 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Co-Delivery of Paclitaxel and siRNA with pH-Responsive Polymeric Micelles for
Synergistic Cancer Therapy
Liuqi Shi, Huayang Feng, Zhanrong Li, Jun Shi, Lin Jin, and Jingguo Li
J. Biomed. Nanotechnol. 17, 322–329 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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–––––––––––––––––––––––––––––––––––– REVIEW ––––––––––––––––––––––––––––––––––––
Injectable Soft Tissue Nano/Micro Fillers for Facial Reconstruction
Yue Pan, Ying Hao, Yao Xiao, Kun Shi, Ying Qu, and ZhiYong Qian
J. Biomed. Nanotechnol. 17, 1–17 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

–––––––––––––––––––––––––––––––––––– ARTICLES ––––––––––––––––––––––––––––––––––––
Oxaliplatin and Gedatolisib (PKI-587) Co-Loaded Hollow Polydopamine Nano-Shells with
Simultaneous Upstream and Downstream Action to Re-Sensitize Drugs-Resistant
Hepatocellular Carcinoma to Chemotherapy
Yin-Ci Zhang, Cheng-Guang Wu, A-Min Li, Yong Liang, Dong Ma, and Xiao-Long Tang
J. Biomed. Nanotechnol. 17, 18–36 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Titanium Dioxide Inhibits Hippocampal Neuronal Synapse Growth Through the
Brain-Derived Neurotrophic Factor-Tyrosine Kinase Receptor B Signaling Pathway
Fashui Hong, Xiao Ze, Xu Mu, and Yuguan Ze
J. Biomed. Nanotechnol. 17, 37–52 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Molecular Mechanism of Bushen Jianpi Inhibition of Postoperative Recurrence and
Metastasis of Hepatocellular Carcinoma
Zhangjie Zhou, Shujuan Fu, Yun Li, Zujun Que, Xinhua Liu, Guanzhen Yu, Dongmei Gao, Zhihui Zhang, Tingting Wu, and Yi Zhong
J. Biomed. Nanotechnol. 17, 53–63 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Apigenin Nanoparticle Attenuates Renal Ischemia/Reperfusion Inflammatory Injury
by Regulation of miR-140-5p/CXCL12/NF-B Signaling Pathway
Xiangfei He, Yibo Wen, Qingwei Wang, Yan Wang, Guoxian Zhang, Junwei Wu, Zhenzhen Li, and Jianguo Wen
J. Biomed. Nanotechnol. 17, 64–77 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Ultrasound-Induced Microbubble Cavitation Combined with miR-34a-Loaded
Nanoparticles for the Treatment of Castration-Resistant Prostate Cancer
Ziqi Wang, Chuanrong Chen, Yuchen Tao, Penglin Zou, Feng Gao, Chao Jia, Long Liu, Gang Li,
GuoXiu Zhang, Yourong Duan, and Qiusheng Shi
J. Biomed. Nanotechnol. 17, 78–89 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes
Triggered with Ultrasound
Safa M. Ben Daya, Vinod Paul, Nahid S. Awad, Nour M. Al Sawaftah, Mohammad H. Al Sayah, and Ghaleb A. Husseini
J. Biomed. Nanotechnol. 17, 90–99 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Plasma-Derived Exosomes Boost the Healing of Irradiated Wound by
Regulating Cell Proliferation and Ferroptosis
Feihong Gan, Raokaijuan Wang, Ping Lyu, Yanxi Li, Ruijie Fu, Yu Du, Ping Gong, and Yang Yao
J. Biomed. Nanotechnol. 17, 100–114 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Hierarchical Microstructure Tailoring of Pure Titanium for Enhancing Cellular Response
at Tissue-Implant Interface
Shokouh Attarilar, Faramarz Djavanroodi, Mahmoud Ebrahimi, Khaled J. Al-Fadhalah, Liqiang Wang, and Masoud Mozafari
J. Biomed. Nanotechnol. 17, 115–130 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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Graphene: Insights on Biological, Radiochemical and Ecotoxicological Aspects
Xing Haixia, Aline Oliveira da Silva de Barros, Francisco do Vale Chaves e Mello, Fan Sozzi-Guo, Cristina Müller,
Sara Gemini-Piperni, Luciana Magalhães Rebelo Alencar, Francisco Franciné Maia Jr., Valder Nogueira Freire,
Frederico Duarte de Menezes, Veronica Aran, Sylvie Devalle, Vivaldo Moura-Neto, Eduardo Ricci-Junior,
Eliete Bouskela, Konstantin Pikula, Kirill Golokhvast, and Ralph Santos-Oliveira
J. Biomed. Nanotechnol. 17, 131–148 (2021)
[Abstract] [Full Text - PDF] [Purchase Article]

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